Compound Q&A
How is Methyl 3-(1H-indol-3-yl)propanoate (CAS: 5548-09-4) typically synthesized?
Answer
Methyl 3-(1H-indol-3-yl)propanoate is typically synthesized via a condensation reaction between 3-indolylmethanone and propionic acid in the presence of a catalyst such as p-TSA or TFA. The reaction is carried out under mild conditions, yielding a product with a purity of around 95%. The reaction is selective and provides good yield.
About
CAS No
5548-09-4
English Name
Methyl 3-(1H-indol-3-yl)propanoate
Molecular Formula
C12H13NO2
Molecular Weight
203.24 g/mol
SMILES
COC(=O)CCC1=CNC2=CC=CC=C21
InChIKey
BAYIDMGOQRXHBC-UHFFFAOYSA-N
Last Updated: 2025-12-26 02:37
