How is 2-[{2-[2-(Dimethylamino)ethoxy]ethyl}(methyl)amino]ethanol (CAS: 83016-70-0) typically synthesized?

2-[{2-[2-(Dimethylamino)ethoxy]ethyl}(methyl)amino]ethanol (CAS: 83016-70-0) is typically synthesized via a multi-step process involving the reaction of 2-(dimethylamino)ethanol with 2-(methoxymethoxy)ethyl chloride followed by methylation. The process involves the use of a phase transfer catalyst, such as tetrabutylammonium bromide, to improve the reaction efficiency. The overall yield is around 75-80%, and the method is selective and mild, providing good control over product purity.