How is Methyl cis-3-hydroxymethylcyclopentane-1-carboxylate (CAS: 58240-93-0) typically synthesized?

Methyl cis-3-hydroxymethylcyclopentane-1-carboxylate is typically synthesized via a condensation reaction between methyl acetoacetate and cyclopentanone in the presence of a Lewis acid catalyst such as aluminium trichloride. The reaction proceeds with high selectivity and yield, producing the desired cis isomer with a yield of over 90%. The reaction conditions are mild, usually carried out at room temperature and under vacuum to remove byproducts.