Compound Q&A

How is Diethyl [(2-chloroethoxy)methyl]phosphonate (CAS: 116384-56-6) typically synthesized?

Answer

Diethyl [(2-chloroethoxy)methyl]phosphonate
Diethyl [(2-chloroethoxy)methyl]phosphonate (CAS: 116384-56-6) is typically synthesized via a multi-step process involving the chlorination of ethylene glycol followed by the reaction with diethyl phosphate. The synthesis often requires mild to moderate conditions and can be catalyzed by phosphorus oxychloride, with yields typically ranging from 70% to 90%. The final product is a clear, colorless to slightly yellow liquid.

About

English Name Diethyl [(2-chloroethoxy)methyl]phosphonate
Molecular Formula C7H16ClO4P
Molecular Weight 230.62799999999996 g/mol
SMILES CCOP(=O)(COCCCl)OCC
InChIKey SRYMPIRBPPQDPD-UHFFFAOYSA-N
Last Updated: 2025-12-25 22:28

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