Compound Q&A

How is 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (CAS: 26662-94-2) typically synthesized?

Answer

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine can be synthesized via a condensation reaction between palmitoyl and oleoyl groups with 1-ethanolamine, followed by phosphorylation. Commonly, this is achieved using catalytic amounts of phosphoric acid and can yield up to 95% of the target compound, with good selectivity.

About

CAS No 26662-94-2
English Name 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine
Molecular Formula C39H76NO8P
Molecular Weight 718.01 g/mol
SMILES CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCN)OC(=O)CCCCCCCC=CCCCCCCCC
InChIKey FHQVHHIBKUMWTI-OTMQOFQLSA-N
Last Updated: 2025-12-25 22:28

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