Compound Q&A
How is Diphenhydramine Citrate (CAS: 88637-37-0) typically synthesized?
Answer
Diphenhydramine Citrate can be synthesized by reacting diphenhydramine hydrochloride with sodium citrate under mild conditions. The reaction involves the substitution of the chloride ion with the citrate group. Common solvents include ethanol or water, and the yield is typically between 80-90%.
About
CAS No
88637-37-0
English Name
Diphenhydramine Citrate
Molecular Formula
C23H29NO8
Molecular Weight
447.48 g/mol
SMILES
OC(=O)C(CC(=O)O)(CC(=O)O)O.CN(CCOC(c1ccccc1)c1ccccc1)C
InChIKey
SPCKHVPPRJWQRZ-UHFFFAOYSA-N
Last Updated: 2025-12-25 18:29
