Compound Q&A

How is 2-(tert-Butyl)-6-chloro-N-methoxy-N-methylbenzo[d]oxazole-7-sulfonamide (CAS: 1206896-20-9) typically synthesized?

Answer

2-(tert-Butyl)-6-chloro-N-methoxy-N-methylbenzo[d]oxazole-7-sulfonamide
2-(tert-Butyl)-6-chloro-N-methoxy-N-methylbenzo[d]oxazole-7-sulfonamide is typically synthesized through a multi-step process involving chlorination of benzo[d]oxazole, followed by methylation and methoximation. This synthesis requires careful control of reaction conditions to ensure high selectivity and yield. Commonly used catalysts include organometallic reagents like tin(II) chloride, and the reaction is usually carried out in anhydrous conditions to minimize side reactions.

About

English Name 2-(tert-Butyl)-6-chloro-N-methoxy-N-methylbenzo[d]oxazole-7-sulfonamide
Molecular Formula C13H17ClN2O4S
Molecular Weight 332.81 g/mol
SMILES CC(C)(C)C1=NC2=C(O1)C(=C(C=C2)Cl)S(=O)(=O)N(C)OC
InChIKey ALPWDUCGTAPWMC-UHFFFAOYSA-N
Last Updated: 2025-12-25 13:43

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