Compound Q&A

How is 2,3-Dihydro-1,4-benzodioxine-5-carbaldehyde (CAS: 29668-43-7) typically synthesized?

Answer

2,3-Dihydro-1,4-benzodioxine-5-carbaldehyde
2,3-Dihydro-1,4-benzodioxine-5-carbaldehyde can be synthesized by the condensation of 2,3-dihydro-1,4-benzodioxin-5-one with formaldehyde in the presence of a strong base such as sodium hydroxide. The reaction is typically carried out in a polar aprotic solvent like dimethylformamide (DMF) at elevated temperature. The yield is generally around 70-80%.

About

CAS No 29668-43-7
English Name 2,3-Dihydro-1,4-benzodioxine-5-carbaldehyde
Molecular Formula C9H8O3
Molecular Weight 164.16 g/mol
SMILES C1COC2=C(C=CC=C2O1)C=O
InChIKey BJXUCBAQZJITKD-UHFFFAOYSA-N
Last Updated: 2025-12-25 13:43

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