Compound Q&A
How is 1-(2-{4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy}ethyl)pyrrolidine (CAS: 116057-75-1) typically synthesized?
Answer
![1-(2-{4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy}ethyl)pyrrolidine](https://static.chemtradehub.com/structs/116/116057-75-1-3eb4.webp "1-(2-{4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy}ethyl)pyrrolidine")
The compound is typically synthesized via a multistep process involving the protection of the amino group, alkylation, olefination, and subsequent deprotection. The synthesis requires careful control of reaction conditions, use of appropriate catalysts, and high selectivity to achieve the desired yield of about 60-70%.
About
CAS No
116057-75-1
English Name
1-(2-{4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy}ethyl)pyrrolidine
Molecular Formula
C28H30INO
Molecular Weight
523.46 g/mol
SMILES
CCC(=C(C1=CC=C(C=C1)OCCN2CCCC2)C3=CC=C(C=C3)I)C4=CC=CC=C4
InChIKey
JJKOTMDDZAJTGQ-DQSJHHFOSA-N
Last Updated: 2025-12-25 08:48
![1-(2-{4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy}ethyl)pyrrolidine — MedChemExpress LLC](https://static.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fd/67ced0fb2b2de6e8e95a67fd-logo.webp){kind=logo}
![1-(2-{4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy}ethyl)pyrrolidine — ShangHaiChuangSai Technology Co Ltd](https://static.chemtradehub.com/suppliers/67cecce82b2de6e8e95a5e02/67cecce82b2de6e8e95a5e02-logo.webp){kind=logo}