Compound Q&A
How is 5-Chloro-2-(trifluoromethyl)pyrimidine (CAS: 845618-08-8) typically synthesized?
Answer
5-Chloro-2-(trifluoromethyl)pyrimidine is usually synthesized via the reaction of 2-chloro-5-trifluoromethylpyridine with ammonia or primary amines. The reaction typically proceeds under basic conditions, with good selectivity and moderate to high yield. Suitable solvents include toluene or other amines.
About
CAS No
845618-08-8
English Name
5-Chloro-2-(trifluoromethyl)pyrimidine
Molecular Formula
C5H2ClF3N2
Molecular Weight
182.532 g/mol
SMILES
FC(F)(F)C1=NC=C(Cl)C=N1
InChIKey
MXCKWZRZRRBNMX-UHFFFAOYSA-N
Last Updated: 2025-12-25 08:48
