Compound Q&A

How is 5-Methyl-1,2,4-oxadiazole-3-carboxylic acid (CAS: 19703-92-5) typically synthesized?

Answer

5-Methyl-1,2,4-oxadiazole-3-carboxylic acid
5-Methyl-1,2,4-oxadiazole-3-carboxylic acid can be synthesized via various methods, including the condensation of 5-methylisoxazole-3-carboxylic acid with hydrogen cyanide followed by hydrolysis. This process yields the target compound with high selectivity and good yield. Other routes involve the reaction of methyl isoxazole-3-carboxylate with methyl isothiocyanate, followed by hydrolysis and oxidation.

About

CAS No 19703-92-5
English Name 5-Methyl-1,2,4-oxadiazole-3-carboxylic acid
Molecular Formula C4H4N2O3
Molecular Weight 128.09 g/mol
SMILES CC1=NC(=NO1)C(=O)O
InChIKey UGENJCBDFKUWDO-UHFFFAOYSA-N
Last Updated: 2025-12-25 08:48

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