Compound Q&A
How is 3-(1,3-Thiazol-2-yl)-1H-indole (CAS: 135531-86-1) typically synthesized?
Answer
3-(1,3-Thiazol-2-yl)-1H-indole can be synthesized through the condensation of indole with 2-thioacetylacetone followed by deprotection. Commonly, this involves the use of a base like sodium hydride and a solvent like dimethylformamide (DMF). The reaction is typically carried out at room temperature, and the yield is around 70-80%.
About
CAS No
135531-86-1
English Name
3-(1,3-Thiazol-2-yl)-1H-indole
Molecular Formula
C11H8N2S
Molecular Weight
200.266 g/mol
SMILES
c1ccc2c(c1)c(c[nH]2)c3nccs3
InChIKey
IYODIJVWGPRBGQ-UHFFFAOYSA-N
Last Updated: 2025-12-25 08:48
