Compound Q&A
How is 2-Methoxy-6-methylnicotinonitrile (CAS: 72918-03-7) typically synthesized?
Answer
2-Methoxy-6-methylnicotinonitrile is commonly synthesized via a multistep process, starting from nicotinonitrile. The key steps involve methylation using methyl triflate as a methylating agent and subsequent methoxylation with methanol in the presence of a base like sodium methoxide. The overall yield is around 85-90% with good selectivity.
About
CAS No
72918-03-7
English Name
2-Methoxy-6-methylnicotinonitrile
Molecular Formula
C8H8N2O
Molecular Weight
137.18 g/mol
SMILES
CC1=NC(=C(C=C1)C#N)OC
InChIKey
IDUHMLQSIWHQKZ-UHFFFAOYSA-N
Last Updated: 2025-12-25 04:58
