Compound Q&A

How is 6-(Benzyloxy)-7-methoxy-4(1H)-quinazolinone (CAS: 286371-64-0) typically synthesized?

Answer

6-(Benzyloxy)-7-methoxy-4(1H)-quinazolinone
6-(Benzyloxy)-7-methoxy-4(1H)-quinazolinone is typically synthesized via the condensation of 2-(benzyloxy)acetyl chloride with 7-methoxyquinazoline in the presence of a base such as triethylamine. The reaction is carried out at room temperature, and the yield is generally good with moderate to high selectivity.

About

English Name 6-(Benzyloxy)-7-methoxy-4(1H)-quinazolinone
Molecular Formula C16H14N2O3
Molecular Weight 282.299 g/mol
SMILES COC1=C(C=C2C(=C1)N=CNC2=O)OCC3=CC=CC=C3
InChIKey UEDIEWQHFJNDTF-UHFFFAOYSA-N
Last Updated: 2025-11-28 19:29

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