Compound Q&A

How is (1H-Pyrrolo[2,3-c]pyridin-2-yl)methanol (CAS: 882881-15-4) typically synthesized?

Answer

(1H-Pyrrolo[2,3-c]pyridin-2-yl)methanol
(1H-Pyrrolo[2,3-c]pyridin-2-yl)methanol (CAS: 882881-15-4) can be synthesized through a multi-step process starting from pyrrole and 2-chloro-3-pyridine methanol. Common methods involve the condensation of pyrrole with 2-chloro-3-pyridine methanol, followed by reduction of the chloride group to achieve the methanol product. The synthesis typically uses palladium catalysts and is carried out in a solvent such as acetonitrile, with high selectivity and yield.

About

English Name (1H-Pyrrolo[2,3-c]pyridin-2-yl)methanol
Molecular Formula C8H8N2O
Molecular Weight 148.17 g/mol
SMILES C1=CN=CC2=C1C=C(N2)CO
InChIKey NLMUSLOQUGZNPN-UHFFFAOYSA-N
Last Updated: 2025-11-28 19:29

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