Compound Q&A

How is N-[2-(1-Cyclohexen-1-yl)ethyl]-2-(4-methoxyphenyl)acetamide (CAS: 51072-34-5) typically synthesized?

Answer

N-[2-(1-Cyclohexen-1-yl)ethyl]-2-(4-methoxyphenyl)acetamide
N-[2-(1-Cyclohexen-1-yl)ethyl]-2-(4-methoxyphenyl)acetamide (CAS: 51072-34-5) is typically synthesized via a multi-step process involving the formation of the cyclohexene derivative, alkylation with the acetyl chloride, and subsequent amide formation. Commonly, this involves the use of sodium hydroxide as a base catalyst to facilitate the amide bond formation. The overall yield is around 70-80%, and the reaction is carried out under inert conditions to avoid side reactions.

About

CAS No 51072-34-5
English Name N-[2-(1-Cyclohexen-1-yl)ethyl]-2-(4-methoxyphenyl)acetamide
Molecular Formula C17H23NO2
Molecular Weight 273.38 g/mol
SMILES COC1=CC=C(C=C1)CC(=O)NCCC2=CCCCC2
InChIKey QIXKSRMRGXDDEH-UHFFFAOYSA-N
Last Updated: 2025-11-28 19:29

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