Compound Q&A

How is 1-Isopropoxy-2-isopropylbenzene (CAS: 14366-59-7) typically synthesized?

Answer

1-Isopropoxy-2-isopropylbenzene
1-Isopropoxy-2-isopropylbenzene can be synthesized via an intramolecular Friedel-Crafts alkylation reaction of isopropylbenzene with isopropyl chloride. The reaction is typically carried out in the presence of a Lewis acid catalyst such as aluminum chloride (AlCl₃). The product is obtained with good selectivity and high yield.

About

CAS No 14366-59-7
English Name 1-Isopropoxy-2-isopropylbenzene
Molecular Formula C12H18O
Molecular Weight 178.27 g/mol
SMILES CC(Oc1ccccc1C(C)C)C
InChIKey KPXDDAHZRPCKJH-UHFFFAOYSA-N
Last Updated: 2025-11-27 23:35

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