Compound Q&A

How is Desacetyl Famciclovir (CAS: 104227-88-5) typically synthesized?

Answer

Desacetyl Famciclovir (Famciclovir Related Compound B)
Desacetyl Famciclovir is synthesized by the acetylation of famciclovir followed by deacetylation at a specific position. The synthesis typically involves the use of acetic anhydride and a catalyst such as pyridine. The final step involves hydrolysis to remove the acetyl group, yielding Desacetyl Famciclovir with a high yield and good selectivity. This process is carried out under an inert atmosphere to avoid decomposition.

About

English Name Desacetyl Famciclovir (Famciclovir Related Compound B)
Molecular Formula C12H17N5O3
Molecular Weight 279.3 g/mol
SMILES CC(=O)OCC(CCN1C=NC2=CN=C(N=C21)N)CO
InChIKey OUMGIMAEASXOJH-UHFFFAOYSA-N
Last Updated: 2025-11-27 19:31

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