Compound Q&A
How is 6-Chloro-1H-indazole-3-carbaldehyde (CAS: 885521-37-9) typically synthesized?
Answer
6-Chloro-1H-indazole-3-carbaldehyde is usually synthesized via the condensation of indole-3-carbaldehyde with chloroacetaldehyde, followed by the removal of the indole group. Commonly used catalysts include acid catalysts like hydrochloric acid or trifluoroacetic acid, which help improve the yield and selectivity of the reaction. The overall yield can be up to 70-80%.
About
CAS No
885521-37-9
English Name
6-Chloro-1H-indazole-3-carbaldehyde
Molecular Formula
C8H5ClN2O
Molecular Weight
180.59 g/mol
SMILES
C1=CC2=C(NN=C2C=C1Cl)C=O
InChIKey
YQELBDVPJNKBAP-UHFFFAOYSA-N
Last Updated: 2025-11-27 19:31
