Compound Q&A
How is 4-[2-(7-Methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]benzenesulfonamide (CAS: 33456-68-7) typically synthesized?
Answer
![4-[2-(7-Methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]benzenesulfonamide](https://static.chemtradehub.com/structs/334/33456-68-7-f4af.webp "4-[2-(7-Methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]benzenesulfonamide")
4-[2-(7-Methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]benzenesulfonamide (CAS: 33456-68-7) can be synthesized through a multi-step process involving the synthesis of the 7-methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydro-2(1H)-isoquinoline intermediate, followed by coupling with the benzene sulfonamide moiety. The reaction typically requires the use of a phase transfer catalyst and takes place in an organic solvent. The yield is generally around 70-80%, with good selectivity for the desired product.
About
CAS No
33456-68-7
English Name
4-[2-(7-Methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]benzenesulfonamide
Molecular Formula
C20H22N2O5S
Molecular Weight
402.47 g/mol
SMILES
CC1(C2=C(C=C(C=C2)OC)C(=O)N(C1=O)CCC3=CC=C(C=C3)S(=O)(=O)N)C
InChIKey
YJHGEYXLMLMFCF-UHFFFAOYSA-N
Last Updated: 2025-11-27 19:31