Compound Q&A
Are there alternatives to Val-Cit-PAB-MMAE (CAS: 644981-35-1) in synthesis?
Answer
There are several alternatives to Val-Cit-PAB-MMAE (CAS: 644981-35-1) in synthesis, including the use of other monoepothilones or modifications of the existing structure. Common substitutes include other MMAE derivatives, such as monomethylauristatin E (MMAE) itself, or related epothilones that offer similar cell cycle arrest properties in cancer therapy.
About
CAS No
644981-35-1
English Name
Val-Cit-PAB-MMAE
Molecular Formula
C58H94N10O12
Molecular Weight
1123.43 g/mol
SMILES
CC[C@@H]([C@H](N(C(=O)[C@H](C(C)C)NC(=O)[C@@H](N(C(=O)OCc1ccc(cc1)NC(=O)[C@@H](NC(=O)[C@H](C(C)C)N)CCCNC(=O)N)C)C(C)C)C)[C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@H](C(=O)N[C@@H]([C@H](c1ccccc1)O)C)C)OC)OC)C
InChIKey
WZEAGSMYTVSXQA-XZZQEHRXSA-N
Last Updated: 2025-11-14 19:17
