Compound Q&A
How is 7-Chloro-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS: 73075-45-3) typically synthesized?
Answer
7-Chloro-1,2,3,4-tetrahydroisoquinoline hydrochloride is typically synthesized via the chlorination of 1,2,3,4-tetrahydroisoquinoline followed by protonation with hydrochloric acid. The reaction is usually carried out under mild conditions, and the yield is around 70-80%. The use of a catalyst such as a Lewis acid can improve selectivity and yield.
About
CAS No
73075-45-3
English Name
7-Chloro-1,2,3,4-tetrahydroisoquinoline hydrochloride (1:1)
Molecular Formula
C9H11Cl2N
Molecular Weight
204.1 g/mol
SMILES
C1CNCC2=C1C=CC(=C2)Cl.Cl
InChIKey
OGIAIXMUSSACDB-UHFFFAOYSA-N
Last Updated: 2025-11-08 00:00
