Compound Q&A

How is 5-Hydroxy-7-(4-hydroxyphenyl)-2,2-dimethyl-3,4-dihydro-2H,6H-pyrano[3,2-g]chromen-6-one (CAS: 63807-90-9) typically synthesized?

Answer

5-Hydroxy-7-(4-hydroxyphenyl)-2,2-dimethyl-3,4-dihydro-2H,6H-pyrano[3,2-g]chromen-6-one
5-Hydroxy-7-(4-hydroxyphenyl)-2,2-dimethyl-3,4-dihydro-2H,6H-pyrano[3,2-g]chromen-6-one (CAS: 63807-90-9) is typically synthesized via a multi-step process involving the condensation of 2,2-dimethylchromen-3-one with 4-hydroxyacetophenone in the presence of a Lewis acid catalyst. The final step involves the reduction of the chromene ring, followed by hydroxylation. The overall yield is around 70%, with high selectivity for the desired dihydro product.

About

CAS No 63807-90-9
English Name 5-Hydroxy-7-(4-hydroxyphenyl)-2,2-dimethyl-3,4-dihydro-2H,6H-pyrano[3,2-g]chromen-6-one
Molecular Formula C20H18O5
Molecular Weight 338.36 g/mol
SMILES CC1(CCc2c(cc3c(c2O)c(=O)c(co3)c4ccc(cc4)O)O1)C
InChIKey BNPMTCOAGXAAIT-UHFFFAOYSA-N
Last Updated: 2025-11-07 19:01

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