Compound Q&A
How is 2-Chloro-1-(5H-chromeno[2,3-b]pyridin-7-yl)-1-propanone (CAS: 146330-68-9) typically synthesized?
Answer
![2-Chloro-1-(5H-chromeno[2,3-b]pyridin-7-yl)-1-propanone](https://static.chemtradehub.com/structs/146/146330-68-9-7a72.webp "2-Chloro-1-(5H-chromeno[2,3-b]pyridin-7-yl)-1-propanone")
2-Chloro-1-(5H-chromeno[2,3-b]pyridin-7-yl)-1-propanone can be synthesized via a multi-step process involving the condensation of 5-chloro-1H-chromeno[2,3-b]pyridin-7-one with an appropriate ketone. The reaction typically requires the use of a catalyst such as a Lewis acid or a base. The overall yield is moderate, around 50-70%, and the method involves careful purification steps to isolate the desired product from byproducts.
About
CAS No
146330-68-9
English Name
2-Chloro-1-(5H-chromeno[2,3-b]pyridin-7-yl)-1-propanone
Molecular Formula
C15H12ClNO2
Molecular Weight
273.72 g/mol
SMILES
CC(Cl)C(=O)C1C=C2CC3=CC=CN=C3OC2=CC=1
InChIKey
JGBGIEPSSRGFBG-UHFFFAOYSA-N
Last Updated: 2025-11-07 19:01
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