Compound Q&A
How is 5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYCYTIDINE (CAS: 666848-11-9) typically synthesized?
Answer
5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYCYTIDINE is typically synthesized via a multi-step process involving protection of the hydroxyl group, introduction of the iodine substituent, and deprotection. Common reagents include tert-butyldimethylsilyl chloride and iodine, with the use of anhydrous conditions and appropriate solvents like dichloromethane.
About
CAS No
666848-11-9
English Name
5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYCYTIDINE
Molecular Formula
C15H26IN3O4Si
Molecular Weight
467.38 g/mol
SMILES
O[C@@H](C[C@H](N1C(N=C(C(I)=C1)N)=O)O2)[C@H]2CO[Si](C)(C(C)(C)C)C
InChIKey
GKUIXIRTAVPIGD-QJPTWQEYSA-N
Last Updated: 2025-11-07 19:01
