Compound Q&A

How is 2-Bromo-6-(trifluoromethoxy)-1,3-benzothiazole (CAS: 628725-99-5) typically synthesized?

Answer

2-Bromo-6-(trifluoromethoxy)-1,3-benzothiazole
2-Bromo-6-(trifluoromethoxy)-1,3-benzothiazole (CAS: 628725-99-5) can be synthesized via a bromination reaction of 6-(trifluoromethoxy)-1,3-benzothiazole with bromine in the presence of a Lewis acid catalyst such as aluminum trichloride. The process involves careful temperature control to ensure selectivity and high yield. The product is then isolated by recrystallization from an appropriate solvent.

About

English Name 2-Bromo-6-(trifluoromethoxy)-1,3-benzothiazole
Molecular Formula C8H3BrF3NOS
Molecular Weight 298.08 g/mol
SMILES C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)Br
InChIKey KDMNQLMJVHMDCQ-UHFFFAOYSA-N
Last Updated: 2025-11-07 19:01

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