Compound Q&A

How is methyl 4-hydroxyoxane-4-carboxylate (CAS: 115996-72-0) typically synthesized?

Answer

methyl 4-hydroxyoxane-4-carboxylate
Methyl 4-hydroxyoxane-4-carboxylate (CAS: 115996-72-0) is typically synthesized through the condensation of methyl 4-chloroxane-1,2-dicarboxylate with sodium hydride in a solvent such as dimethylformamide (DMF). The reaction involves the displacement of the chlorine atom with a hydroxyl group, yielding the desired product in good yield. This synthesis is conducted under anhydrous conditions to prevent side reactions.

About

English Name methyl 4-hydroxyoxane-4-carboxylate
Molecular Formula C7H12O4
Molecular Weight 160.17 g/mol
SMILES COC(=O)C1(CCOCC1)O
InChIKey YMKUGBABAIVMLG-UHFFFAOYSA-N
Last Updated: 2025-11-07 19:01

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