Compound Q&A

How is Dimethyl isopropylmalonate (CAS: 51122-91-9) typically synthesized?

Answer

Dimethyl isopropylmalonate
Dimethyl isopropylmalonate can be synthesized through the reaction of isopropylmalononitrile with methyl iodide in the presence of a base like potassium carbonate. The method involves protecting the carboxylic acid group and then converting it to the corresponding ester. The reaction yields a high purity product with good selectivity and high yield.

About

CAS No 51122-91-9
English Name Dimethyl isopropylmalonate
Molecular Formula C8H14O4
Molecular Weight 174.2 g/mol
SMILES CC(C)C(C(=O)OC)C(=O)OC
InChIKey HVNFMZHHKRLLNH-UHFFFAOYSA-N
Last Updated: 2025-11-07 19:01

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