Compound Q&A

How is 1,1',1''-(Chloromethanetriyl)tris(4-methoxybenzene) (CAS: 49757-42-8) typically synthesized?

Answer

1,1',1''-(Chloromethanetriyl)tris(4-methoxybenzene)
1,1',1''-(Chloromethanetriyl)tris(4-methoxybenzene) can be synthesized by reacting 4-methoxybenzene with chloromethane in the presence of a Lewis acid catalyst, such as aluminum chloride. The reaction is carried out under anhydrous conditions to prevent side reactions. The yield is typically good, and the product is isolated by column chromatography using an appropriate solvent system.

About

CAS No 49757-42-8
English Name 1,1',1''-(Chloromethanetriyl)tris(4-methoxybenzene)
Molecular Formula C22H21ClO3
Molecular Weight 368.86 g/mol
SMILES COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)Cl
InChIKey OBFCMKPFILBCSQ-UHFFFAOYSA-N
Last Updated: 2025-11-07 19:01

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