Compound Q&A
How is 2-(4-Piperidinyloxy)pyrimidine (CAS: 499240-48-1) typically synthesized?
Answer
2-(4-Piperidinyloxy)pyrimidine can be synthesized through a multi-step process involving the reaction of 4-hydroxypiperidine with 2-bromopyrimidine in the presence of a base such as potassium carbonate. The reaction is typically performed in an aprotic solvent like dimethylformamide (DMF) at elevated temperatures. The product is isolated by crystallization from a suitable solvent, and the purity is confirmed by spectroscopic techniques.
About
CAS No
499240-48-1
English Name
2-(4-Piperidinyloxy)pyrimidine
Molecular Formula
C9H13N3O
Molecular Weight
179.22 g/mol
SMILES
C1CNCCC1OC2=NC=CC=N2
InChIKey
IAFUZCLDORRBJY-UHFFFAOYSA-N
Last Updated: 2025-11-07 15:33
