Compound Q&A
How is BODIPY-FL NHS ester (CAS: 146616-66-2) typically synthesized?
Answer
BODIPY-FL NHS ester (CAS: 146616-66-2) is typically synthesized by first protecting the BODIPY core with a hydroxyl group, then converting it to an acetylated derivative. This is followed by esterification with NHS ester to yield the final product. Common solvents include dichloromethane, and the reaction proceeds via a nucleophilic substitution mechanism. Yield is generally around 75-85%, and the reaction is catalyzed by a suitable base or acid depending on the specific step.
About
CAS No
146616-66-2
English Name
BODIPY-FL NHS ester
Molecular Formula
C18H18BF2N3O4
Molecular Weight
389.2 g/mol
SMILES
[B-]1(N2C(=CC(=C2C=C3[N+]1=C(C=C3)CCC(=O)ON4C(=O)CCC4=O)C)C)(F)F
InChIKey
SDVMGNSTOAJONW-UHFFFAOYSA-N
Last Updated: 2025-11-07 12:11
