Compound Q&A

How is (2S)-2-Piperazinylacetonitrile dihydrochloride (CAS: 2158301-19-8) typically synthesized?

Answer

(2S)-2-Piperazinylacetonitrile dihydrochloride
(2S)-2-Piperazinylacetonitrile dihydrochloride is typically synthesized by the reaction of (S)-2-piperazinylacetonitrile with hydrochloric acid in an aqueous medium. The process involves careful control of pH and temperature to ensure the formation of the dihydrochloride salt. The yield is generally around 85-90%, and the reaction is highly selective.

About

English Name (2S)-2-Piperazinylacetonitrile dihydrochloride
Molecular Formula C6H13Cl2N3
Molecular Weight 89.95 g/mol
SMILES Cl.Cl.N#CC[C@H]1CNCCN1
InChIKey YHCNTTLRKUTDRD-ILKKLZGPSA-N
Last Updated: 2025-11-07 12:11

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