Compound Q&A
How is Methyl (2Z)-(6-hydroxy-1-benzofuran-3(2H)-ylidene)acetate (CAS: 726174-52-3) typically synthesized?
Answer
Methyl (2Z)-(6-hydroxy-1-benzofuran-3(2H)-ylidene)acetate is synthesized via the condensation of 6-hydroxy-1-benzofuran-3-one with acetaldehyde, catalyzed by a Lewis acid like aluminum trichloride. The reaction is conducted in anhydrous conditions, and the product is isolated by recrystallization. The yield is around 75-80% with good selectivity towards the desired isomer.
About
CAS No
726174-52-3
English Name
Methyl (2Z)-(6-hydroxy-1-benzofuran-3(2H)-ylidene)acetate
Molecular Formula
C11H10O4
Molecular Weight
206.2 g/mol
SMILES
COC(=O)Cc1coc2cc(O)ccc12
InChIKey
WAYZUAFLMLFPIM-QPJJXVBHSA-N
Last Updated: 2025-11-07 12:11
