Compound Q&A
How is 4-(3-Amino-1,2,4-triazin-6-yl)-2-fluorobenzonitrile (CAS: 1197377-47-1) typically synthesized?
Answer
4-(3-Amino-1,2,4-triazin-6-yl)-2-fluorobenzonitrile is typically synthesized by the reaction of 2-fluorobenzonitrile with 1,2,4-triazine-3(2H)-thione in the presence of a suitable base such as sodium hydride. The reaction is carried out at room temperature, and the product can be isolated by recrystallization from an appropriate solvent. The yield is usually around 70-80%, with excellent selectivity and purity.
About
CAS No
1197377-47-1
English Name
4-(3-Amino-1,2,4-triazin-6-yl)-2-fluorobenzonitrile
Molecular Formula
C10H6FN5
Molecular Weight
204.21 g/mol
SMILES
C1=CC(=C(C=C1C2=CN=C(N=N2)N)F)C#N
InChIKey
JXQHTMHBDHVPDQ-UHFFFAOYSA-N
Last Updated: 2025-11-07 12:11
