Compound Q&A

How is 4-(Bromomethyl)benzo[d][1,3]dioxole (CAS: 101417-40-7) typically synthesized?

Answer

4-(Bromomethyl)benzo[d][1,3]dioxole
4-(Bromomethyl)benzo[d][1,3]dioxole (CAS: 101417-40-7) is typically synthesized through a bromination reaction of 4-hydroxymethylbenzo[d][1,3]dioxole with hydrogen bromide in the presence of a Lewis acid catalyst, such as aluminum bromide (AlBr₃). The reaction is exothermic and requires careful control of temperature to achieve high yield and selectivity.

About

English Name 4-(Bromomethyl)benzo[d][1,3]dioxole
Molecular Formula C8H7BrO2
Molecular Weight 215.05 g/mol
SMILES C1OC2=CC=CC(=C2O1)CBr
InChIKey NXSORIZRMNGQNL-UHFFFAOYSA-N
Last Updated: 2025-11-07 12:11

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