Compound Q&A

How is 4-(4H-1,2,4-Triazol-4-yl)phenol (CAS: 98581-86-3) typically synthesized?

Answer

4-(4H-1,2,4-Triazol-4-yl)phenol
4-(4H-1,2,4-Triazol-4-yl)phenol (CAS: 98581-86-3) is typically synthesized through a multistep process involving the condensation of 4-bromoacetophenone with azide followed by reduction and deprotection. Commonly used catalysts include palladium-based catalysts, and the reaction is carried out under mild conditions to ensure selectivity and yield. Detailed protocols can be found in the literature and can be adapted for industrial scale production.

About

CAS No 98581-86-3
English Name 4-(4H-1,2,4-Triazol-4-yl)phenol
Molecular Formula C8H7N3O
Molecular Weight 161.16 g/mol
SMILES C1=CC(=CC=C1N2C=NN=C2)O
InChIKey RIBPDWQKLGLSLS-UHFFFAOYSA-N
Last Updated: 2025-11-07 12:11

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