Compound Q&A

How is Ethyl 1-cyclopropyl-8-ethoxy-6,7-difluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate (CAS: 172602-83-4) typically synthesized?

Answer

Ethyl 1-cyclopropyl-8-ethoxy-6,7-difluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate
Ethyl 1-cyclopropyl-8-ethoxy-6,7-difluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate is typically synthesized via a multistep process involving the protection of the hydroxyl group, followed by the introduction of the cyclopropyl and fluoro groups, and finally the introduction of the ethoxy group. This process often involves the use of protecting agents like tert-butyldimethylsilyl chloride and catalysts such as palladium(II) acetate for cross-coupling reactions.

About

English Name Ethyl 1-cyclopropyl-8-ethoxy-6,7-difluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate
Molecular Formula C17H17F2NO4
Molecular Weight 337.32 g/mol
SMILES CCOC(=O)c1cn(C2CC2)c2c(c1=O)cc(c(c2OCC)F)F
InChIKey HVSSSDATQQUFJP-UHFFFAOYSA-N
Last Updated: 2025-11-05 07:29

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