Compound Q&A

How is 3-Fluoro-4-(trifluoromethoxy)phenol (CAS: 177596-38-2) typically synthesized?

Answer

3-Fluoro-4-(trifluoromethoxy)phenol
3-Fluoro-4-(trifluoromethoxy)phenol is typically synthesized through the chlorination of 4-(trifluoromethoxy)phenol followed by a substitution reaction with fluoroamine. Commonly used catalysts include bases like sodium hydride. The reaction yields a high purity product with good selectivity and yield.

About

English Name 3-Fluoro-4-(trifluoromethoxy)phenol
Molecular Formula C7H4F4O2
Molecular Weight 196.1 g/mol
SMILES C1=CC(=C(C=C1O)F)OC(F)(F)F
InChIKey UTFSPWRTXCDUIJ-UHFFFAOYSA-N
Last Updated: 2025-11-05 07:29

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