Compound Q&A

How is (1-(tert-Butoxycarbonyl)-6-methoxy-1H-indol-2-yl)boronic acid (CAS: 850568-65-9) typically synthesized?

Answer

(1-(tert-Butoxycarbonyl)-6-methoxy-1H-indol-2-yl)boronic acid
(1-(tert-Butoxycarbonyl)-6-methoxy-1H-indol-2-yl)boronic acid is commonly synthesized via a boronate ester formation step, starting from 6-methoxy-1H-indole and tert-butoxycarbonyl chloride. The reaction is typically performed in the presence of a base such as triethylamine, and the product is isolated and purified using standard techniques like column chromatography.

About

English Name (1-(tert-Butoxycarbonyl)-6-methoxy-1H-indol-2-yl)boronic acid
Molecular Formula C14H18BNO5
Molecular Weight 291.11 g/mol
SMILES B(C1=CC2=C(N1C(=O)OC(C)(C)C)C=C(C=C2)OC)(O)O
InChIKey ATIJYIUOXDCYTN-UHFFFAOYSA-N
Last Updated: 2025-11-05 07:29

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