Compound Q&A

How is (2R)-2-Methoxy-1-propanol (CAS: 6131-59-5) typically synthesized?

Answer

(2R)-2-Methoxy-1-propanol
(2R)-2-Methoxy-1-propanol can be synthesized via the reaction of methanol with propene in the presence of a catalytic amount of sulfuric acid or phosphoric acid. Another method involves the reaction of tert-butyl alcohol with methanol in the presence of a strong acid like hydroiodic acid or hydrobromic acid. The yield and selectivity of these reactions depend on the reaction conditions and choice of catalyst.

About

CAS No 6131-59-5
English Name (2R)-2-Methoxy-1-propanol
Molecular Formula C4H10O2
Molecular Weight 90.12 g/mol
SMILES CO[C@H](C)CO
InChIKey YTTFFPATQICAQN-SCSAIBSYSA-N
Last Updated: 2025-11-05 07:29

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