Compound Q&A

How is Sodium (2S)-2-(tetradecanoylamino)propanoate (CAS: 67395-95-3) typically synthesized?

Answer

Sodium (2S)-2-(tetradecanoylamino)propanoate
Sodium (2S)-2-(tetradecanoylamino)propanoate is typically synthesized by the reaction of sodium hydroxide with tetradecanoyl chloride. The process involves the addition of the sodium salt to the chloroform solution of the carboxylic acid chloride, followed by a neutralization step using an appropriate base. The yield is usually around 85-90%, and the reaction is carried out under anhydrous conditions to avoid hydrolysis.

About

CAS No 67395-95-3
English Name Sodium (2S)-2-(tetradecanoylamino)propanoate
Molecular Formula C17H32NNaO3
Molecular Weight 321.4 g/mol
SMILES CCCCCCCCCCCCCC(=O)NC(C)C(=O)[O-].[Na+]
InChIKey KCPRYTSOOWAFQV-RSAXXLAASA-M
Last Updated: 2025-11-05 07:29

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