Compound Q&A
How is (3E)-4-ethoxy-1,1,1-trifluorobut-3-en-2-one (CAS: 59938-06-6) typically synthesized?
Answer
(3E)-4-Ethoxy-1,1,1-trifluorobut-3-en-2-one is often synthesized via the reaction of trifluoroacetyl chloride with ethoxyacetic acid, followed by hydrolysis. The reaction is typically catalyzed using a strong base like sodium hydroxide, and the product is isolated by recrystallization from an appropriate solvent. This method provides good yield and selectivity.
About
CAS No
59938-06-6
English Name
(3E)-4-ethoxy-1,1,1-trifluorobut-3-en-2-one
Molecular Formula
C6H7F3O2
Molecular Weight
168.11 g/mol
SMILES
CCOC=CC(=O)C(F)(F)F
InChIKey
YKYIFUROKBDHCY-ONEGZZNKSA-N
Last Updated: 2025-11-05 07:29
