Compound Q&A
How is 2-{[(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy}ethanol ethanedioate (CAS: 1215268-15-7) typically synthesized?
Answer
![2-{[(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy}ethanol ethanedioate (1:1)](https://static.chemtradehub.com/structs/121/1215268-15-7-27fa.webp "2-{[(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy}ethanol ethanedioate (1:1)")
2-{[(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy}ethanol ethanedioate (CAS: 1215268-15-7) is typically synthesized via a multistep process involving the protection of the amino group, followed by esterification and acid catalyzed rearrangement. The yield is around 85% with a high degree of selectivity.
About
CAS No
1215268-15-7
English Name
2-{[(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy}ethanol ethanedioate (1:1)
Molecular Formula
C12H21NO8
Molecular Weight
307.3 g/mol
SMILES
CC1(O[C@H]2[C@@H](C[C@@H]([C@H]2O1)OCCO)N)C.C(=O)(C(=O)O)O
InChIKey
HIQMXNAXTWONJI-WZSOELRKSA-N
Last Updated: 2025-11-05 07:29
![2-{[(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy}ethanol ethanedioate (1:1) — ShangHaiYiJiShengWuKeJiYouXianGongSiXiaoShouBu](https://static.chemtradehub.com/suppliers/67cecfe92b2de6e8e95a656d/67cecfe92b2de6e8e95a656d-logo.webp){kind=logo}
![2-{[(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy}ethanol ethanedioate (1:1) — Jin Jinle (Hunan) Chemical Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce76192b2de6e8e95a464e/67ce76192b2de6e8e95a464e-logo.webp){kind=logo}