Compound Q&A
How is 1-(Bromomethyl)-2-(methylsulfonyl)benzene (CAS: 82657-74-7) typically synthesized?
Answer
1-(Bromomethyl)-2-(methylsulfonyl)benzene is typically synthesized through the reaction of 2-(methylsulfonyl)benzyl bromide with benzene. This process involves the bromination of the methylsulfonylbenzyl group followed by the coupling with benzene. The reaction is performed under basic conditions, and the yield is around 70-80%. Suitable catalysts include sodium hydride or potassium tert-butoxide.
About
CAS No
82657-74-7
English Name
1-(Bromomethyl)-2-(methylsulfonyl)benzene
Molecular Formula
C8H9BrO2S
Molecular Weight
249.13 g/mol
SMILES
CS(=O)(=O)c1ccccc1CBr
InChIKey
ZBLBWTFICJOODX-UHFFFAOYSA-N
Last Updated: 2025-11-05 07:29
