Compound Q&A
How is N,N-Bis(2-hydroxyethyl)-4-methylbenzenesulfonamide (CAS: 7146-67-0) typically synthesized?
Answer
N,N-Bis(2-hydroxyethyl)-4-methylbenzenesulfonamide can be synthesized by reacting 4-methylbenzenesulfonic acid with ethylene glycol in the presence of a strong base such as potassium hydroxide. The reaction proceeds via a nucleophilic substitution mechanism, yielding the desired amide product with good selectivity and yield. Conditions are typically carried out at elevated temperatures and under inert atmosphere to prevent side reactions.
About
CAS No
7146-67-0
English Name
N,N-Bis(2-hydroxyethyl)-4-methylbenzenesulfonamide
Molecular Formula
C11H17NO4S
Molecular Weight
259.33 g/mol
SMILES
CC1=CC=C(C=C1)S(=O)(=O)N(CCO)CCO
InChIKey
NHFJDXPINIIUQG-UHFFFAOYSA-N
Last Updated: 2025-11-05 07:29
