Compound Q&A

How is 2-Amino-7-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-iodo-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one (CAS: 114748-67-3) typically synthesized?

Answer

2-Amino-7-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-iodo-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
This compound is typically synthesized through a multi-step reaction involving the coupling of an amino compound with a furan derivative, followed by iodination and a series of cyclization reactions. The synthesis often requires the use of catalysts and specific reagents to achieve high yields and selectivity. Precise control over reaction conditions is essential for obtaining the desired product.

About

English Name 2-Amino-7-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-iodo-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
Molecular Formula C11H13IN4O3
Molecular Weight 376.15 g/mol
SMILES Nc1nc2c(c(=O)[nH]1)c(cn2[C@H]1CC[C@H](O1)CO)I
InChIKey KJNOBXXCZQLWLF-CAHLUQPWSA-N
Last Updated: 2025-11-04 22:31

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