Compound Q&A

How is 2,7-Dimethylquinoline (CAS: 93-37-8) typically synthesized?

Answer

2,7-Dimethylquinoline
2,7-Dimethylquinoline is typically synthesized by the condensation of 2-methylquinoline with formaldehyde in the presence of a strong acid catalyst such as hydrochloric acid. This reaction yields 2,7-dimethylquinoline with good selectivity and a high yield of up to 95%. Other methods include the reduction of 2,7-dimethylquinone or the treatment of 2,7-dimethylisoquinoline with sodium hydride.

About

CAS No 93-37-8
English Name 2,7-Dimethylquinoline
Molecular Formula C11H11N
Molecular Weight 157.22 g/mol
SMILES CC1=CC2=C(C=C1)C=CC(=N2)C
InChIKey QXKPLNCZSFACPU-UHFFFAOYSA-N
Last Updated: 2025-11-04 22:31

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