How is 2-(2-pyridyl)pyridin-4-amine (CAS: 14151-21-4) typically synthesized?

2-(2-pyridyl)pyridin-4-amine is commonly synthesized via the amidation of 2-pyridylpyridine with an appropriate amine reagent in the presence of a catalyst such as anhydrous sodium carbonate or triethylamine. The reaction involves the formation of an intermediate imine, which is reduced to the amine product. High yields and good selectivity can be achieved under optimized conditions.