Compound Q&A
How is 2-Amino-5-methyl-1,3-thiazole-4-carboxylic acid (CAS: 688064-14-4) typically synthesized?
Answer
2-Amino-5-methyl-1,3-thiazole-4-carboxylic acid is commonly synthesized through the condensation of 5-methylthiazole-2-carbaldehyde with ammonia or an amine. The reaction typically employs a mild base like potassium carbonate to enhance the nucleophilicity of the amine. The yield is generally around 70-80%, with good control over the regioselectivity.
About
CAS No
688064-14-4
English Name
2-Amino-5-methyl-1,3-thiazole-4-carboxylic acid
Molecular Formula
C5H6N2O2S
Molecular Weight
158.18200000000002 g/mol
SMILES
CC1=C(N=C(S1)N)C(=O)O
InChIKey
BAANOAVDEBKXEY-UHFFFAOYSA-N
Last Updated: 2025-11-04 13:04
