Compound Q&A

How is 3-(Chloromethyl)-1H-pyrazole hydrochloride (CAS: 69658-97-5) typically synthesized?

Answer

3-(Chloromethyl)-1H-pyrazole hydrochloride (1:1)
3-(Chloromethyl)-1H-pyrazole hydrochloride is typically synthesized by the reaction of 3-chloromethylpyrazole with hydrochloric acid. This process involves heating 3-chloromethylpyrazole with concentrated hydrochloric acid to produce the hydrochloride salt. The reaction is exothermic and requires proper cooling to maintain optimal conditions. The yield is generally high, and the product is purified by recrystallization from water.

About

CAS No 69658-97-5
English Name 3-(Chloromethyl)-1H-pyrazole hydrochloride (1:1)
Molecular Formula C4H6Cl2N2
Molecular Weight 153.01 g/mol
SMILES C1=C(NN=C1)CCl.Cl
InChIKey IPKKDQOUBFUVGT-UHFFFAOYSA-N
Last Updated: 2025-11-04 13:04

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